Microfluidic Sperm Sorting Chips

FERTILE® provides a better process for sperm washing, swimming and gradient centrifuging, making these processes with less time and stage demanding. It also sorts sperms with best DNA and physiological quality.!

Our Publications

See our latest article published on Human Reproduction Journal!

Molly M. Quinn,Liza Jalalian,Salustiano Ribeiro, Katherine Ona, Utkan Demirci, Marcelle Cedars, and Mitchell P. Rosen

Microfluidic Sorting Selects Sprem for Clinical Use with Reduced DNA Damage Compared to Density Gradient Centrifugation with Swim-Up in Split Semen Samples

Human Reproduction, pp. 1-6, 2018

STUDY QUESTON

Does microfluidic sorting improve the selection of sperm with lower DNA fragmentation over standard densitygradient centrifugation?

SUMMARY ANSWER

Microfluidic sorting of unprocessed semen allows for the selection of clinically usable, highly motile sperm with nearly undetectable levelsof DNA fragmentation.

WHAT IS KNOWN

Microfluidic devices have been explored to sort motile and morphologically normal sperm from a raw sample without centrifugation; however, it is uncertain whether DNA damage is reduced in this process.

Fertile® Technology

FERTILE®, can be used in IVF (In vitro fertilization), IUI (Intra uterine insemination), ICSI (Intracytoplasmic sperm injection).

FERTILE® provides a better process for sperm washing, swimming and gradient centrifuging, making these processes with less time and stage demanding.

It also sorts sperms with best DNA and physiological quality.

utkan-demirci

Utkan DEMİRCİ, Ph.D.

Co-Founder, Scientific Advisor

Dr. Demirci is currently an associate professor at Stanford University School of Medicine, Canary Center Early Cancer Detection.

umut-gurkan

Umut GÜRKAN, Ph.D.

Scientific Advisor

Umut A. Gurkan is leading the CASE Biomanufacturing and Microfabrication Laboratory (CASE-BML) at Case Western Reserve University (CWRU).

As a result of KOEK LABS innovative works, development of microchip technology has been achieved using determine with antigen-antibody interactions and ambient temperature for counting, relasing of label free live cells.

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